A clinical case of atypical course and difficulties in diagnosing Hodgkin's lymphoma

Hodgkin's lymphoma (LH) is a B-cell malignant lymphoproliferative disease. There are no specific symptoms characteristic only for this Here may be an asymptomatic increase in peripheral lymph nodes; of intoxication (B-symptoms — fever above 38 ° C at least three consecutive days without signs inflammation; night profuse sweats; weight loss by 10% body over the past 6 months); intermittent fever; itching; patients with massive mediastinal lesion chest pain, cough, shortness breath, compression superior vena cava, localization closer to sternum, discomfort behind sternum possible. The presence formation mediastenia and purulent process (abscess, phlegmons, osteomyelitis), resistant surgery (autopsy, drainage, resection) antibacterial therapy requires exclusion neoplastic process. It necessary carefully observe technique performing biopsy transporting material neutral formalin solution early date pathological - anatomical laboratory, case non-standard manifestations disease, revision mandatory immunohistochemical examination. important bear mind that comorbidity (obesity, hypertension, diabetes mellitus) creates additional objective difficulties diagnosis treatment, collegial decision consultation specialists patient management tactics.